Lüsen is a comune and village situated in the province of Bozen-Bolzano in the autonomous province of South Tyrol, Italy. It is located approximately 40 kilometres (25 mi) northeast of the city of Bolzano.
The municipality serves as a local administrative division within the mountainous region of the Italian Alps. While it functions as a distinct village community, it is defined by its geographical proximity to the regional hub of Bolzano.