Santa Domenica Vittoria is a town and comune located in the Metropolitan City of Messina in Sicily, southern Italy. It is situated at an elevation of 1,080 metres (3,540 ft) above sea level within the Nebrodi Mountains Range.
The town is positioned approximately 7 kilometres (4 mi) north of Randazzo and offers views over the northern Etna Valley. Despite its administrative location in the Metropolitan City of Messina, it utilizes the telephone prefix for the Metropolitan City of Catania due to its position on the border between the two entities.