Santa Caterina Villarmosa is a comune, or municipality, situated in the Province of Caltanissetta within the Italian region of Sicily. It serves as a local administrative division located in the southern portion of the island.
The town is positioned approximately 80 kilometres (50 mi) southeast of Palermo and about 13 kilometres (8 mi) north of Caltanissetta. It is characterized by its location within the interior province of Sicily, providing a geographic link between these major regional centers.