Palazzolo Acreide is a town and comune located in the Province of Syracuse within the region of Sicily, Italy. Situated in the Hyblean Mountains, it lies approximately 43 kilometres (27 mi) from the city of Syracuse.
The town is recognized as one of the "Borghi più belli d'Italia," a designation highlighting its status as one of the most beautiful villages in the country. It serves as a notable destination within the Sicilian landscape, characterized by its historical setting and geographical location in the mountainous interior.