Nuxis is a town and comune situated in the Province of Sulcis Iglesiente within the autonomous island region of Sardinia, Italy. Geographically, it is positioned approximately 35 kilometres (22 mi) west of Cagliari and about 20 kilometres (12 mi) east of Carbonia.
The municipality has a population of 1,382 inhabitants. It serves as a local administrative center within the Sulcis Iglesiente province.