Castel del Giudice is a comune, or municipality, situated in the Province of Isernia within the Molise region of Italy. It is located in the interior of the country, positioned approximately 50 kilometres (31 mi) northwest of Campobasso and about 30 kilometres (19 mi) north of Isernia.
As a local administrative division, the town serves as a settled community within the Molise region. It is defined by its geographic placement between the provincial capitals of Campobasso and Isernia.