Melissa is a feminine given name of Greek origin. The name is derived from the Greek word μέλισσα (mélissa), which translates to "bee." This term further originates from the word μέλι (meli), meaning "honey."
The etymology of the name also finds roots in Hittite, where the word melit signifies "honey." While Melissa is a common variant form of the name, other recognized variations include Malissa, Melesa, Melessa, Meliza, Mellisa, Melosa, and Molissa.