Casole Bruzio is a town located in the province of Cosenza within the Calabria region of southern Italy. Historically, it functioned as an independent comune until 2017.
Following a referendum held in 2017, Casole Bruzio ceased to be an independent municipality and became a frazione of the newly formed municipality of Casali del Manco. This merger involved the unification of five former municipalities into a single administrative entity.