Sant'Eusanio del Sangro is a municipality located in the province of Teramo, within the Abruzzo region of central Italy. It is situated in an area characterized by its proximity to the Adriatic coast and the surrounding Apennine Mountains.
The town serves as a local residential and agricultural hub. While it maintains a traditional Italian rural character, it is primarily known for its geographical position within the historical landscape of the Abruzzo region.