Santa Cruz La Laguna is a municipality situated on the northern shore of Lago de Atitlán in the Sololá department of Guatemala. The municipality is composed of the villages of Santa Cruz La Laguna and Tzununá, along with four smaller settlements known as caseríos.
The area is populated almost entirely by the Kaq'chikel indigenous Maya people. As of 2018, the estimated population of the municipality was 9,392 residents.