Santa Cruz del Quiché is a city located in Guatemala with a population of 78,279. Situated at an elevation of 2,021 meters above sea level, it serves as the capital of the El Quiché department and functions as the municipal seat of the Santa Cruz del Quiché municipality.
The city is located at coordinates 15.03°N 91.15°W. It features transportation infrastructure including Quiché Airport, which is situated just south of the city limits.