San Andrés Itzapa is a town located in the eastern region of the Chimaltenango department in Guatemala. It serves as part of a municipality that covers a total area of 63.7 km2.
The town has a population of 24,992, while the broader municipality has a total population of 32,083. Geographically, San Andrés Itzapa is situated with the district capital to its north, Acatenango to its south, and Parramos to its east.