Hôpital Saint-Louis is a hospital located in the 10th arrondissement of Paris, France. It is situated at 1 avenue Claude-Vellefaux, near the Goncourt metro station.
The facility was constructed in 1611 by architect Claude Vellefaux following a request from King Henry IV of France. Today, it operates as part of the Assistance publique - Hôpitaux de Paris hospital system.