Klötze is a town located in the Altmarkkreis Salzwedel district within the state of Saxony-Anhalt, Germany. It is situated approximately 20 km northwest of Gardelegen and 35 km northeast of Wolfsburg.
The town was first mentioned in historical records in 1144 under the name Cloetze, which translates to "wooden block." In January 2010, Klötze expanded its jurisdiction by absorbing 11 former municipalities following the disbanding of the Verwaltungsgemeinschaft of Klötze.