Kizilsu Kyrgyz Autonomous Prefecture is an autonomous prefecture located in western Xinjiang, China. It serves as a border region adjacent to both Kyrgyzstan and Tajikistan. The administrative capital of the prefecture is Artush.
The prefecture covers a total area of 70,916 km2 (27,381 sq mi) and has a population of approximately 622,222 people. While Uyghurs constitute the largest ethnic group in the region, making up nearly two-thirds of the population, the prefecture is also home to most of the Kyrgyz people residing in China, who account for slightly over a quarter of the total inhabitants.