Penco is a city and commune located in the Concepción Province of Chile's Bío Bío Region. It is situated on the Bay of Concepción.
Founded on February 12, 1550, by Pedro de Valdivia as the city of Concepción del Nuevo Extremo, Penco is recognized as the third oldest city in Chile. It follows the capital, Santiago, founded in 1541, and La Serena, founded in 1544.