Otse is a village situated in the South-East District of Botswana. It is located approximately 60 km south of the capital city, Gaborone, along the Gaborone–Lobatse road and in close proximity to the border with South Africa.
The village is home to the Balete people, who share ancestral ties with those residing in Ramotswa, Gabane, and Mogobane. According to the 2011 census, the population of Otse was 7,636.